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Disclosure of interest: Xiao Wang: nothing to disclose E-Posters - RISK FACTORS - PRIMARY AND SECONDAR PREVENTION 05.00 - RISK FACTORS AND PREVENTION (PRIMARY AND SECONDARY) - 05.03 - EPIDEMIOLOGY & RISK FACTORS P2515 - ESOC25-1203 GUT MICROBIOTADEPENDENT TRIMETHYLAMINE N-OXIDE AND COGNITIVE FUNCTION OVER THREE YEARS AFTER MILD-TO MODERATE ISCHEMIC STROKE - PROSCIS B Thomas Liman 1 , Naomi Giesers 2 , Arash Haghikia 3 , Ulf Landmesser 4 , Stanley Hazen 5 , Matthias Endres 6 1 University of Oldenburg, Charit Universittsmedizin Berlin, Oldenburg, Germany, 2 University of Oldenburg, Oldenburg, Germany, 3 Ruhr University Bochum, Bochum, Germany, 4 Charit Universittsmedzin Berlin, Berlin, Germany, 5 Department of Cellular and Molecular Medicine, Cleveland Clinic, Cleveland, United States, 6 Charit Universittsmedizin Berlin, Dept of neurology, Berlin, Germany Background and Aims: Gut microbiotadependent metabolites, in particular trimethylamine n-oxide (TMAO) have been identified as promoters of atherosclerosis

HMB: A leucine metabolite known for muscle growth enhancement and breakdown prevention

Published protocols using BPC-157 and TB-500 in combination typically follow a loading phase of daily or every-other-day administration for 2-4 weeks, followed by reduced frequency for maintenance

[19] The onset may be vague and slow and the condition can be confused with other conditions, and there may be few to many symptoms without anemia

Results were strongest in those with milder gingival inflammation (80% improved) and far lower in patients presenting with frank desquamative gingivitis (29% improved)