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The study examines the impact of mood-stabilizing medications, including lithium, valproate (VPA), carbamazepine (CBZ), and lamotrigine (LTG), on dendritic growth and synaptic protein expression in primary hippocampal neurons

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Significantly elevated Hcy associated with the 677TT variant appears to trigger hypermethylation via an alternative B2 dependent rescue pathway (Fryar-Williams, 2016)