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Given the rich lipid content of the nervous system, hemoglobin-derived iron works with lipid peroxidation to induce ferroptosis, which eventually leads to neuronal mitochondrial damage, edema, and apoptosis of neurons and astrocytes

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Berk M, Williams LJ, Jacka FN, ONeil A, Pasco JA, Moylan S, Allen NB, Stuart AL, Hayley AC, Byrne ML, Maes M (2013) So depression is an inflammatory disease, but where does the inflammation come from

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After 2 week acute toxicity and cumulative tests in mice, no statistical difference existed between LAAM GSH-CQD group and normal control group in the parameters from complete blood count and serum biochemistry analyses (Supplementary Fig