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Kokura, S., Wolf, R.E., Yoshikawa, T., Granger, D.N

Measuring the expression levels of genes such as TFRC or SLC7A11 in brain tissue or blood from patients with neurodegenerative diseases could provide clues for assessing ferroptotic activity and disease progression (49)

doi:10.1152/physrev.1985.65.2.238

However, when the body is subjected to severe viral infections, environmental toxins, or chronic inflammation, this ratio can plummet dramatically, indicating that the cellular defense systems are overwhelmed and failing to keep pace with the influx of free radicals

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