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Importantly, hydrogen selenide and its activated form selenophosphate and other reactive low molecular mass (LMM) chemical species of Se are thought to be relevant to the majority of Se biological activity being metabolic precursors of selenoproteins (Loef et al., 2011

Graying occurs when the melanocytes (cells responsible for hair color) stop producing melanin or when hydrogen peroxide builds up in the hair follicle, essentially "bleaching" the hair from the inside out

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a low level of oxidants, as well as the chemicals (diethyl maleate and acetaminophen) that specifically react with and deplete cellular GSH, extend the lifespan 8,26,27