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Scientific References Frequently Asked Questions Can you have too much vitamin B12

Subjective sleep and awakening quality showed mixed results, with some improvement observed in patients but no significant changes or a tendency towards deterioration in healthy individuals

The practical takeaway: AOD-9604 has a clean safety profile in trials but a failed Phase 2b efficacy endpoint

Because B12 is water-soluble, your body uses what it needs and passes most of the excess, and there is no established upper intake limit because harmful effects from high intake have not been well documented