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Am J Clin Nutr 2011;94:104-111

Oral treatments that have been proven not to work include: Oral vitamin E Oral tamoxifen Oral procarbazine Oral omega-3 fatty acids Oral vitamin E with L-carnitine There are other oral treatments that need more study to see if they work

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LeeJETitcombTJBishtBRubensteinLMLouisonRWahlsTL.A modified mct-based ketogenic diet increases plasma beta-hydroxybutyrate but has less effect on fatigue and quality of life in people with multiple sclerosis compared to a modified paleolithic diet: A waitlist-controlled, randomized pilot study

Also, the percentage of mean change was calculated for each subject from baseline to week 5 and from baseline to week 10, and then MannWhitney test was employed to determine the difference in the mean of the percentage of mean difference between the two groups