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Indeed, there may be benefits to lower MPO activity

In the CNS during ageing and due to its high energy requirement, a greater accumulation of ROS will occur, leading to an increase in oxidative damage, altering mitochondrial function, neurogenesis, and the normal cell cycle (Spalding et al., 2013

This stimulus amplitude fluctuated between 0.5 mA (Jongkees et al., 2018) and 12 mA (Trevizol et al., 2016), similar to the range reported in other literature

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