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It is also well known that an essential feature of cancer cells resulting from their anomalous metabolic processes is an increased redox level, which leads to the production of high levels of intracellular GSH (0.63.1 mM) [35]

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It was also reported that HIF-2 promoted CPT1A-mediated -oxidation, and therefore it was identified as the central mediator of the ferroptosis of chondrocytes