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A crucial next step in drug development, several experts told Undark, is to test for safety and efficacy in humans

Cell (2010) 140:80520.10.1016/j.cell.2010.01.022 28 NewtonKDixitVM

4ad and Supplementary Fig

Aging and low-grade inflammation reduce renal function in middle-aged and older adults in Japan and the USA

In general, it is not obvious how the distinction is made between what determines true sensor/receptor processes and what are determined by the intrinsic kinetic features of the dynamic interactions that arise through shared intermediates, whether of the membrane voltage or of common pools of ions in each compartment