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After 810 days growth, the cultures were shaken for 1 h (180 rpm, 37 C) to remove the microglia, then were shaken for 14 h (200 rpm, 37 C) to collect the OPCs

Research has shown that Nestorone, a progesterone analog, upregulates SIRT3 and restores the acetyl-superoxide dismutase 2 (Ac-SOD2)/superoxide dismutase 2 (SOD2) ratio by modulating the progesterone signaling pathway

[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Chen CR, Malik M, Snyder M, Drlica K

NMDA currents and receptor protein are downregulated in the amygdala during maintenance of fear memory