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(2016), allows human iPSC to form a layer of stem cells, the neuroepithelium, from which neuronal precursors differentiate and self-organize into multiple brain-like sub-regions

Acetyl-CoA derived from FAO not only fuels the TCA cycle to support additional ATP production but also contributes to the synthesis of mitochondrial phospholipids such as cardiolipin, which is indispensable for maintaining inner membrane integrity and respiratory efficiency

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Urinary lactate serves as both an early diagnostic biomarker for hypoxic-ischemic encephalopathy in term infants and a strong predictor of long-term neurodevelopmental outcomes in preterm brain injury, potentially mediated by impaired cerebral energy metabolism during early neurodevelopment (Zasada et al