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Furthermore, phosphorylated JNK induces oxidative stress, mitochondrial membrane permeability, and dysfunction through the activation of Bax, the translocation of Bax to the mitochondria, the opening of the mitochondrial permeability transition pore, and Src-dependent inhibition of the electron transport complex

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The degradation results in the formation of methyl-galacturonate which is converted into L-galactonate via two reactions catalyzed by methyl esterase and D-galacturonate reductase

This study aims to investigate the mechanisms by which astaxanthin alleviates oxidative stress and inflammatory damage induced by thermal stress

[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Stanley CA, Lieu YK, Hsu BY, et al