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These biological factors, if unaccounted for, may confound disease-specific metabolic signatures and complicate downstream analyses

Pallav Sengupta, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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While the bone marrow and hematopoietic cells are most affected, other organs involved in hematopoiesis, such as the thymus and spleen, also sustain injury due to IR [64, 65]

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