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[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Gargiulo S, Gamba P, Testa G, Rossin D, Biasi F, Poli G, Leonarduzzi G

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COX-derived reactive species and transcriptional activity of interleukin-1beta ( IL-1 ), interleukin-6 ( IL-6 ), tumor necrosis factor- ( TNF- ), cyclooxygenase-2 ( COX-2 ), and inducible nitric oxide synthase ( iNOS ) are increased during aging (Michaud et al., 2013