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de Oliveira FA, et al

It is interesting to note that although KO mice for GH receptor/GH binding protein and for GH-releasing hormone showed an extended longevity (250, 251), this effect was not observed when using targeted deletion of the GH receptor in the liver, muscle, or adipose tissue (Table 3) (252)

-arrestins regulate gonadotropin receptor-mediated cell proliferation and apoptosis by controlling different FSHR or LHCGR intracellular signaling in the hGL5 cell line