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Dendritic and macrophage inflammatory responses are also mitigated by LIF expression [60, 61]

Western blot analysis Cell extracts were prepared with RIPA buffer containing proteases and phosphatase inhibitors and the concentration of cell lysates was determined using the Bradford protein assay reagent (Bio-Rad)

Supplementary Table S3-1 ) directly binding with MD-2 which confirmed the synergistic activation of hyperglycaemia driven MD2, TLR4 and the AGEs, leading towards the establishment of worsened myocardial injury

Co-activator A protein that increases gene transcription by interacting with a transcription factor