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Functionally, Vangl1 depletion mirrors E6/E7 loss in CaSki spheroids by disrupting spheroid architecture, reducing invasiveness, and increasing chemosensitivity

Anti-inflammatory Effects: It can reduce liver inflammation, which is critical for conditions like non-alcoholic fatty liver disease (NAFLD)

We performed de novo resistance studies with HCV replicons and NGS analysis of samples from BEM monotherapy clinical studies (NCT03219957) to establish BEMs resistance profile

Like taxanes, vinca alkaloids (vincristine, vinblastine) are anti-mitotic agents that target microtubules, however, these inhibit polymerization (57)

coli compared to their linear counterparts, albeit with increased hemolysis (Mohammed et al., 2022)