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Yang, H., et al., Nrf1 and Nrf2 regulate rat glutamate-cysteine ligase catalytic subunit transcription indirectly via NF-kappaB and AP-1

By triggering ferroptosis, -elemene improves the susceptibility of KRAS-mutant CRC cells to cetuximab, suggesting a potential therapeutic option for RAS-mutated CRC patients

Rai, V., Yadav, U., Kumar, P., Yadav, S

The use of additional ROS sensors as well as a combination of transgenic reporters and ROS-producing enzymes in a cell and compartment specific manner may be highly informative to decipher ROS signaling