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Si una lesin del labio es nueva y est creciendo, tiene bordes desiguales, contiene varios colores o sangra sin causa aparente, un dermatlogo debe evaluarla

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The functional activity of epithelial melanocytes is regulated by the reciprocal interaction of melanocytes in the basal cell layer of the epithelium with the underlying lamina-proprial connective tissue and by several other biological agents

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Because it acts on the central nervous system rather than the circulatory system, it provides a distinct therapeutic approach