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TBK1: a new player in ALS linking autophagy and neuroinflammation

doi: 10.1080/1028415X.2022.2143958 124

D1467G does not affect NS3 helicase or ATPase activity We next analysed whether D1467G would affect NS3 helicase activity in vitro, thereby explaining the impact of this mutation on () strand synthesis

Validation & quality assurance The final stages involve human validation, where domain experts manually review filtered data to identify nuances and contextual errors that automated systems might miss

Additional studies have highlighted the neuroprotective effects of other natural compounds, such as benzyl ITC and indole-3-carbinol (not an ITC, but derived from indole glucosinolates), in preclinical models of PD