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doi: 10.1038/s41598-020-78003-z 191 MortenKJBadderLKnowlesHJ

In ovarian cancer, tumor-released mesothelin, which is linked to a glycosylphosphatidylinositol (GPI) anchor, binds to MR on macrophages, driving their polarization toward the TAM phenotype, which supports tumor growth and suppresses the immune response

Single-cell transcriptomic and lineage-tracing analyses suggest that resident macrophages mainly contribute to TAM pools within omental metastases and milky spots, whereas monocyte-derived macrophages dominate in ascites [20,73]

Short-term effects of metformin and myo-inositol in women with polycystic ovarian syndrome (PCOS): a meta-analysis of randomized clinical trials

Fu, M., Zhang, W., Wu, L., Yang, G., Li, H