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Their high specificity for target receptors or enzymes often results in fewer off-target effects and improved safety profiles

During ferroptosis, triggering stimuli can activate the process of ferritin degradation, termed ferritinophagy, or lead to the degradation of SLC40A1, thereby augmenting the levels of cytoplasmic Fe 2+ within unstable iron pools in cancer cells [104,105,106]

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Sekhar RV, Patel SG, Guthikonda AP, Reid M, Balasubramanyam A, Taffet GE, et al

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