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Drug class: Benzodiazepine antagonist

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lactis Probio-M8) with dopamine agonists improved non-motor symptoms such as cognitive function, bowel regularity, and overall gut health (Sun et al., 2021)

This likely reflects a loss of IL33-producing basal cells and may contribute to the regeneration defects upon CSE exposure which we previously described in the same culture system 61

Of note, RBC-associated drugs have a longer life span in circulation compared to the ones portioned in plasma because they are protected by RBCs from macrophage uptake, the liver metabolism, and renal clearance