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Research progress of quercetin in cardiovascular disease

Gut-derived TMAO induces apoptosis by increasing intracellular mROS levels and further promoting NLRP3 assembly activation, with the underlying mechanism being the regulation of the intracellular mROS-NLRP3 axis to activate cytokinesis and release inflammatory factors, thus promoting DKD (Yi et al., 2023)

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From the perspective of clinical practice and dietary recommendation, our findings do not support a beneficial association of l-carnitine with CVD and its risk factors, but suggest potential harm

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