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Description

at lower translational requirements, LAP is in the foreground [12]

The mechanism of NET formation involves NADPH oxidase- and peptidylarginine deiminase 4 (PAD4)-mediated citrullination of histones, translocation of neutrophil NE and MPO to the nucleus, chromatin decondensation and extracellular DNA release promoted by proteolysis of histones

Annu Rev Microbiol

von HS, Morley JE, Anker SD

The treatment was well-tolerated, resulting in mild fever (grade I CRS) and no signs of immune effector cell-associated neurotoxicity syndrome (ICANS)