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Glutamate consumption by aminotransferases to generate NEAAs has also been indicated to be required for tumor growth in diverse cancer types 29,40,41,42

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Compound 48 exhibited the most favorable binding energy at 9.2 kcal/mol, slightly better than the reference ligand triclosan (9.1 kcal/mol), while 47 scored 8.5 kcal/mol

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