whats is glutathione

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10.1016/s1875-5364(15)60003-6 [DOI] [PubMed] [Google Scholar] Yook J

Curr Pharm Des (2011) 17(23):24217

Studies have shown that the intracellular LIP level is regulated by ferritin (Reichert et al., 2020), and in ferroptosis, ferritinophagy increases LIP ( 2 O 2 oxidizes Fe 2+ to Fe 3+ via the Fenton reaction, forming the highly active hydroxyl radical (OH), inducing oxidative stress and leading to ferroptosis, the accumulation of lipoid-OOH, and the oxidation of polyunsaturated fatty acids (PUFAs) (Qi et al., 2020)