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Disease-modifying medications control major flares, but baseline joint stiffness and pain persist, particularly in the hands and wrists

It is a common cause of macrocytic (megaloblastic) anemia and, in advanced cases, pancytopenia

Some folks also dig alternative and complementary therapies like yoga, behavioral therapy, acupuncture, or massage therapy.

While Levodopa remains the gold standard, its limitations necessitate combination therapy and adjunct modalities such as deep brain stimulation and nanocarrier-based drug delivery