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Collagen and elastin synthesis observed in in vitro skin fibroblast models

Step 6: Insert the Needle at the Correct Angle For a half-inch needle, insert at 45 degrees to the skin surface when using the pinch technique or when injecting at a lean site

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Possible side effects include: Redness Itching Tingling Dryness Peeling Mild stinging Breakouts or small bumps Bruising or pain with injectable use Allergy-type reactions such as hives or swelling Stop using the product and seek medical care if you notice hives, swelling, trouble breathing, severe irritation, or symptoms that feel unusual for you