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384 This was shown to improve folding of a mechanosensitive channel protein (MscL) in PURE

The results of the current study are in agreement with previous results from both clinical and pre-clinical TBI studies, which showed that NAA is decreased following injury [15, 62, 67]

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Data synthesis The studies varied in terms intervention type, dosage regimens, duration of treatment, study design, and participant characteristics such as disease stage and concurrent medication hence given the substantial heterogeneity, a quantitative meta-analysis was not performed

TABLE 2 Research related to TMAO and human or animal chronic kidney disease models