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Thus, energy deprivation along with increased levels of harmful factors, either intracellular or extracellular, disrupts neuronal homeostasis

10.1124/dmd.108.020552 17 WadhwaS.SinghalS.RawatS

It is acylated at the N-terminus with a C20 fatty diacid linked via a -glutamic acid spacer, and carries an intramolecular disulfide bond between Cys3 and Cys8 structural modifications that extend its half-life and reduce fibril formation relative to native amylin

doi: 10.3389/fphar.2017.00643

S8A): To distinguish between forming fibers and blood vessels in images stained for collagen 1 or 3, a segmentation mask for blood vessels was created using a threshold value of 0.9 on the red channel image