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F., Yoshino, J., Bruzzone, S., Sociali, G., Tokizane, K., Lei, H

Two cysteine residues (Cys35 and Cys105), identified in the DNA binding domain of HSF1, directly affect the cellular redox state via the induction of antioxidant genes (Barna et al

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Biochemical analyses indicated that THPE2-F has promise as a therapeutic agent for DR, given its capacity to restore GSH levels and to regulate iron levels under hyperglycemic conditions in DR mice (147)