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Clinicialtrials.gov (2020)

For example, as one of the significantly expressed miRNAs, miR-30e-5p was involved in the prevention of tumor growth and angiogenesis in gallbladder cancer via the PI3K/Akt pathway (Wang et al., 2020

Concurrently, altered glucose metabolism in the orbitofrontal cortex and limbic regions reflects energy deficits and mitochondrial dysfunction, contributing to the severity of psychiatric symptoms, such as paranoia, agitation, and mood disturbances ( MRI studies have further identified gray matter atrophy in the prefrontal cortex, medial cingulate gyrus, and hippocampus, regions that are critically involved in memory, decision-making, and emotional regulation (Thompson et al., 2004)

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Improved insights into key factors that influence the individual-specific response to antibiotics and dietary intervention may lead to better efficacy in reversing or preventing antibiotic-induced microbial dysbiosis as well as strategies for preventing cardiometabolic diseases