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The compounds effects on NAD+ metabolism may have implications for muscle biology given the importance of NAD+-dependent enzymes in muscle function

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5-Amino-1MQ is an oral NNMT (nicotinamide N-methyltransferase) inhibitor that works by blocking an enzyme that depletes cellular NAD+ and SAM

It exhibits an IC 50 of approximately 1 M for NNMT inhibition 4 , with favorable pharmacokinetic properties