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DOI: Posadino, A.M., Cossu, A., Giordo, R., Piscopo, A., Abdel-Rahman, W

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In PCOS granulosa cells, elevated phosphorylation of the pro-apoptotic protein BAX, coupled with suppressed phosphorylation of the anti-apoptotic protein BCL-2, enhances mitochondrial pathway apoptosis, accelerating follicular atresia ( 3.6 Chronic low-grade inflammation Chronic low-grade inflammation have been identified as a central component in the pathogenesis of PCOS, rather than mere accompanying phenomena

doi: 10.1002/rmv.2403 418 AlkafaasSSAbdallahAMHussienAMBedairHAbdoMGhoshSet al