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5662 NAC therapy is recommended in such clinical scenarios, to overcome the reported incidence rates of 60% for severe hepatotoxicity and 5% for mortality

Mosharov, E., Cranford, M

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Employing digital PCR (dPCR) and next-generation sequencing to longitudinally quantify mtDNA mutations in paired peripheral blood, tissue biopsies, and CSF will clarify their roles in residual inflammation, neurocognitive decline, and immunological failure