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Furthermore, the allocation to acetylsalicylic acid was associated with an increased risk of major bleeding and a decreased risk of thromboembolic complications [64]

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174,175 Several oncogenic mechanisms, such as the transcription factor HIF-1, PI3K/Akt/mTOR pathway and c-Myc, upregulate genes encoding glucose transporters and glycolytic proteins, including GLUT1, GLUT3, and lactate dehydrogenase (LDH)