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Ethical approval The study was conducted in accordance with the ethical principles that have their origin in the Declaration of Helsinki

Yuen PC, Taddei CR, Wyka BE et al

This integrated strategy acknowledges that oxidative stress requires diverse solutions tailored to individual circumstancesfrom daily maintenance to acute challenges, and through all stages of liferecognizing the mutually reinforcing relationship between these different antioxidant mechanisms rather than viewing them as competitive alternatives.

10.1016/j.jaad.2017.12.004 131 TomlinsonI

XO inhibitors are also being studied as a possible treatment for reperfusion injury