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Nausea, vomiting, and diarrhea beyond normal adaptation responses can occur with excessive doses

due to their biological characteristics, these bacteria can survive and reproduce in the host with a weakened immune system and even break through the intestinal barrier to cause bacteremia

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Knee osteoarthritis has doubled in prevalence since the mid-20th century

2-methoxyestradiol (2-ME), a metabolite of 17--estradiol synthesized by Catechol-O-Methyltransferase (COMT), induces the differentiation of the endovascular cytotrophoblast cells into its invasive phenotype under the condition of hypoxia (75)