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Savitz J, Drevets WC, Smith CM, Victor TA, Wurfel BE, Bellgowan PS et al (2015)

Similar results were reported in the clinical study of patients with type 2 diabetes, where increased TMAO levels are independently associated with risks of adverse cardiovascular events (138, 139)

The obtained data showed that although the calculated association constant was comparable in all three experiments, the dissociation constant (kd) was 9 times higher when the elution buffer 2 containing EDTA was used as dissociation buffer compared to the experiment in which binding buffer was used as elution buffer