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Relationship between peripheral blood biomarkers and brain GSH Data of 25 immunoinflammatory blood biomarkers were available for 13 HC and 14 MA users in our study (see Supplementary Table 2)

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Gemcitabine induces CAFs to secrete exosomes containing miR-3173-5p, which inhibits the expression of ACSL4, thereby decreasing PUFA binding to phospholipids and enhancing resistance to ferroptosis in PDAC cells [41, 42]

Probably, if all cysteine residues were in the reduced form (with free sulfhydryl groups) high percentage of helical fragments would be possible

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