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NMN supplementation in mice also improved mitochondrial morphology through DRP1, and reduced ROS through antioxidant response expression 113

Although there was no involvement of circular RNA in our study, DCM was associated with left ventricular diastolic dysfunction (LVDV: SMD: 4.93, 95%CI 3.35, 6.50, p = 0.00001) followed by systolic dysfunction (LVSV: SMD: -1.38, 95%CI -1.38, 4.13, p = 0.33) between the DCM and the healthy control groups which confirm the establishment of DCM in mouse models which gradually progress into DCM in both mice and the humans

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Artificial intelligence tool for optimizing eligibility screening for clinical trials in a large community cancer center, JCO Clin