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17 Dietary manipulations through dietary restriction and supplementation with folic acid and antioxidants (e.g., N-acetylcysteine, acetyl-L-carnitine, alpha-lipoic acid, glutathione, Ginkgo biloba ) to promote successful brain aging are being studied

Epigenetics 10, 698707

This was an unexpected result insofar that GPX3 is considered a classical Nrf2-induced gene and TNF- has repeatedly been reported to upregulate other Nrf2 target genes in various cell types including leukocytes of the myeloid lineage, vascular endothelial cells, and osteoblasts 50,51,52,53,54