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doi: 10.1016/j.sjbs.2015.08.002

Indeed, FECH protein is downregulated in several models of Fe-S cluster depletion 71,72,73

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This leaves first-line therapies ineffective and give patients only a limited number of second-line treatment options

Oral drug delivery utilizing nanoparticles exhibits superior bioavailability, extended residence time, and enhanced biodistribution compared to free drugs (183185)