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Another study in the Journal of the American Medical Association notes that among those with diabetic nephropathy (loss of kidney function due to diabetes), combining vitamin B6 (25 mg) and folic acid (2.5 mg) (B-complex vitamin) with 1,000 mcg of oral B12 per day for six years increases the risk of cardiovascular events, including heart attack and stroke

Don't worry Hi i have same problem feel awful for few days after been on shots for 7 years Hard too explain Not what you're looking for

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You want to first wash your hands thoroughly, and then be gentle as you wash your face so as not to rub vigrously or manipulate the filler (for the first 36 hours after injection) and to not irritate or rub into the injection insertion points

While I cant say exactly how much you should be using I can give you some pertinent information that will help guide you