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Future Perspective This review summarizes a relation between catalase and the pathogenesis of some critical diseases such as diabetes, Parkinson's disease, acatalasemia, vitiligo, and Alzheimer's disease

There is substantial evidence indicating that AKT signaling is able to phosphorylate STAT3 protein although sometimes there is no specification on whether AKT directly phosphorylated STAT3 or whether the activation was induced indirectly through the activation of mTOR or PKM2 (see below)