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Unlike compounds such as vitamin E or beta-carotene, AST readily crosses the bloodbrain barrier and acts across both hydrophilic and lipophilic environments, enabling broad neuroprotective effects

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Due to this variability in the cholesterol content of LDL particles, the concentration of LDL-C does not accurately reflect the quantity of existing particles (LDL-P), especially in the following situations: Family history of atherosclerotic cardiovascular risk High triglycerides Low levels of HDL cholesterol Metabolic syndrome Diabetes mellitus Recurrent events due to atherosclerotic cardiovascular risk despite lifestyle changes and/or hypolipidemic therapy Hence, a high number of LDL-P can be associated with normal LDL-C concentrations, indicating an excess of small-sized particles with low cholesterol content but high atherogenic potential