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In animal models of ischemic stroke, VEGF has been shown to improve neuronal survival, reduce infarct size, and enhance cognitive function

We, therefore, used alternative approaches and have determined the structure of a high molecular weight TrxR subfamily member using cryo-EM, demonstrating the feasibility of this methodology to study this protein subfamily of importance in several human diseases (PDB ID 8A1R, EMD-15084) (Fig

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2d, e) whilst Peredox responded similarly in both strains (Fig