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10.1038/nsmb.2372 46 KrolJ.LoedigeI.FilipowiczW

Lancet 388: 797805, 2016

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however, this is based on anecdotal evidence, and clinical trials have not shown any benefit over biosynthetic forms

Additionally, it was reported that BRAF inhibition in therapy-sensitive cells induced downregulation of the lipogenic regulator sterol regulatory element-binding protein 1 and thereby lipogenesis